Usefulness of micro-arrays technology in ethiological diagnosis of eosinophilic esophagitis

Background Eosinophilic esophagitis (EoE) is an immune-mediated disease of the esophagus characterized by symptoms related to esophageal disfunction and histollogically by an eosinophil-predominat inflammation. Multiple therapies have been suggested to be helpful in EoE including endoscopic dilation, medical therapy and withdrawal dietary but, the election of what food should be excluded is very difficult. Component-resolved diagnosis and microarray technology have been recently introduced into clinical allergy practice, and may be particularly useful in foodsensitized allergic patients. We used microarrays methods in EoE to find specific food proteins or epitopes possibly implicated in this disease.